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Gut-derived Enterococcus faecium from ulcerative colitis patients promotes colitis in a genetically susceptible mouse host

BACKGROUND: Recent metagenomic analyses have revealed dysbiosis of the gut microbiota of ulcerative colitis (UC) patients. However, the impacts of this dysbiosis are not fully understood, particularly at the strain level. RESULTS: We perform whole-genome shotgun sequencing of fecal DNA extracts from...

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Detalles Bibliográficos
Autores principales: Seishima, Jun, Iida, Noriho, Kitamura, Kazuya, Yutani, Masahiro, Wang, Ziyu, Seki, Akihiro, Yamashita, Taro, Sakai, Yoshio, Honda, Masao, Yamashita, Tatsuya, Kagaya, Takashi, Shirota, Yukihiro, Fujinaga, Yukako, Mizukoshi, Eishiro, Kaneko, Shuichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6876129/
https://www.ncbi.nlm.nih.gov/pubmed/31767028
http://dx.doi.org/10.1186/s13059-019-1879-9