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Rhes, a striatal-enriched protein, promotes mitophagy via Nix

Elimination of dysfunctional mitochondria via mitophagy is essential for cell survival and neuronal functions. But, how impaired mitophagy participates in tissue-specific vulnerability in the brain remains unclear. Here, we find that striatal-enriched protein, Rhes, is a critical regulator of mitoph...

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Detalles Bibliográficos
Autores principales: Sharma, Manish, Ramírez-Jarquín, Uri Nimrod, Rivera, Oscar, Kazantzis, Melissa, Eshraghi, Mehdi, Shahani, Neelam, Sharma, Vishakha, Tapia, Ricardo, Subramaniam, Srinivasa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6876193/
https://www.ncbi.nlm.nih.gov/pubmed/31676548
http://dx.doi.org/10.1073/pnas.1912868116