Low-Concentration PTX And RSL3 Inhibits Tumor Cell Growth Synergistically By Inducing Ferroptosis In Mutant p53 Hypopharyngeal Squamous Carcinoma

INTRODUCTION: RSL3-induced ferroptosis is a cell death pathway dependent upon intracellular iron and is characterized by accumulation of lipid hydroperoxides. Glutaminolysis, a glutamine-fueled intracellular metabolic pathway, is an essential pathway of ferroptosis in cancer cells. Recent findings s...

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Detalles Bibliográficos
Autores principales: Ye, Jing, Jiang, Xiaohua, Dong, Zhihuai, Hu, Sunhong, Xiao, Mang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2019
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6876222/
https://www.ncbi.nlm.nih.gov/pubmed/31819616
http://dx.doi.org/10.2147/CMAR.S217944

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6876222/
https://www.ncbi.nlm.nih.gov/pubmed/31819616
http://dx.doi.org/10.2147/CMAR.S217944

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