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SHH signaling mediated by a prechordal and brain enhancer controls forebrain organization
Sonic hedgehog (SHH) signaling plays a pivotal role in 2 different phases during brain development. Early SHH signaling derived from the prechordal plate (PrCP) triggers secondary Shh induction in the forebrain, which overlies the PrCP, and the induced SHH signaling, in turn, directs late neuronal d...
Autores principales: | Sagai, Tomoko, Amano, Takanori, Maeno, Akiteru, Ajima, Rieko, Shiroishi, Toshihiko |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
National Academy of Sciences
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6876251/ https://www.ncbi.nlm.nih.gov/pubmed/31685615 http://dx.doi.org/10.1073/pnas.1901732116 |
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