Over-Expression of Inhibitor of Differentiation 2 Attenuates Post-Infarct Cardiac Fibrosis Through Inhibition of TGF-β1/Smad3/HIF-1α/IL-11 Signaling Pathway

Background: Cardiac fibrosis after myocardial infarction mainly causes cardiac diastolic and systolic dysfunction, which results in fatal arrhythmias or even sudden death. Id2, a transcriptional repressor, has been shown to play an important role in the development of fibrosis in various organs, but...

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Detalles Bibliográficos
Autores principales: Yin, Lin, Liu, Ming-xin, Li, Wei, Wang, Feng-yuan, Tang, Yan-hong, Huang, Cong-xin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6876274/
https://www.ncbi.nlm.nih.gov/pubmed/31803053
http://dx.doi.org/10.3389/fphar.2019.01349

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6876274/
https://www.ncbi.nlm.nih.gov/pubmed/31803053
http://dx.doi.org/10.3389/fphar.2019.01349

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