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Stellate Cells, Hepatocytes, and Endothelial Cells Imprint the Kupffer Cell Identity on Monocytes Colonizing the Liver Macrophage Niche

Macrophages are strongly adapted to their tissue of residence. Yet, little is known about the cell-cell interactions that imprint the tissue-specific identities of macrophages in their respective niches. Using conditional depletion of liver Kupffer cells, we traced the developmental stages of monocy...

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Detalles Bibliográficos
Autores principales: Bonnardel, Johnny, T’Jonck, Wouter, Gaublomme, Djoere, Browaeys, Robin, Scott, Charlotte L., Martens, Liesbet, Vanneste, Bavo, De Prijck, Sofie, Nedospasov, Sergei A., Kremer, Anna, Van Hamme, Evelien, Borghgraef, Peter, Toussaint, Wendy, De Bleser, Pieter, Mannaerts, Inge, Beschin, Alain, van Grunsven, Leo A., Lambrecht, Bart N., Taghon, Tom, Lippens, Saskia, Elewaut, Dirk, Saeys, Yvan, Guilliams, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6876284/
https://www.ncbi.nlm.nih.gov/pubmed/31561945
http://dx.doi.org/10.1016/j.immuni.2019.08.017