Cargando…
Stellate Cells, Hepatocytes, and Endothelial Cells Imprint the Kupffer Cell Identity on Monocytes Colonizing the Liver Macrophage Niche
Macrophages are strongly adapted to their tissue of residence. Yet, little is known about the cell-cell interactions that imprint the tissue-specific identities of macrophages in their respective niches. Using conditional depletion of liver Kupffer cells, we traced the developmental stages of monocy...
Autores principales: | Bonnardel, Johnny, T’Jonck, Wouter, Gaublomme, Djoere, Browaeys, Robin, Scott, Charlotte L., Martens, Liesbet, Vanneste, Bavo, De Prijck, Sofie, Nedospasov, Sergei A., Kremer, Anna, Van Hamme, Evelien, Borghgraef, Peter, Toussaint, Wendy, De Bleser, Pieter, Mannaerts, Inge, Beschin, Alain, van Grunsven, Leo A., Lambrecht, Bart N., Taghon, Tom, Lippens, Saskia, Elewaut, Dirk, Saeys, Yvan, Guilliams, Martin |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cell Press
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6876284/ https://www.ncbi.nlm.nih.gov/pubmed/31561945 http://dx.doi.org/10.1016/j.immuni.2019.08.017 |
Ejemplares similares
-
Bone marrow-derived monocytes give rise to self-renewing and fully differentiated Kupffer cells
por: Scott, Charlotte L., et al.
Publicado: (2016) -
Niche signals and transcription factors involved in tissue-resident macrophage development
por: T'Jonck, Wouter, et al.
Publicado: (2018) -
Osteopontin Expression Identifies a Subset of Recruited Macrophages Distinct from Kupffer Cells in the Fatty Liver
por: Remmerie, Anneleen, et al.
Publicado: (2020) -
The Transcription Factor ZEB2 Is Required to Maintain the Tissue-Specific Identities of Macrophages
por: Scott, Charlotte L., et al.
Publicado: (2018) -
Hepatocarcinoma Induces a Tumor Necrosis Factor-Dependent Kupffer Cell Death Pathway That Favors Its Proliferation Upon Partial Hepatectomy
por: Hastir, Jean-François, et al.
Publicado: (2020)