Tanshinone IIA reverses EGF- and TGF-β1-mediated epithelial-mesenchymal transition in HepG2 cells via the PI3K/Akt/ERK signaling pathway

Epithelial-to-mesenchymal transition (EMT) is an essential phenotypic conversion involved in cancer progression. Epidermal growth factor (EGF) and transforming growth factor (TGF)-β1 are potent inducers of the EMT. Tanshinone IIA (Tan IIA) is a phenanthrenequinone extracted from the root of Salvia m...

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Detalles Bibliográficos
Autores principales: Zhang, Longkai, Lin, Weibin, Chen, Xiaodan, Wei, Gang, Zhu, Hailong, Xing, Shangping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2019
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6876303/
https://www.ncbi.nlm.nih.gov/pubmed/31807174
http://dx.doi.org/10.3892/ol.2019.11032

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6876303/
https://www.ncbi.nlm.nih.gov/pubmed/31807174
http://dx.doi.org/10.3892/ol.2019.11032

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