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MutL sliding clamps coordinate exonuclease-independent Escherichia coli mismatch repair

A shared paradigm of mismatch repair (MMR) across biology depicts extensive exonuclease-driven strand-specific excision that begins at a distant single-stranded DNA (ssDNA) break and proceeds back past the mismatched nucleotides. Historical reconstitution studies concluded that Escherichia coli (Ec)...

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Detalles Bibliográficos
Autores principales: Liu, Jiaquan, Lee, Ryanggeun, Britton, Brooke M., London, James A., Yang, Keunsang, Hanne, Jeungphill, Lee, Jong-Bong, Fishel, Richard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6876574/
https://www.ncbi.nlm.nih.gov/pubmed/31757945
http://dx.doi.org/10.1038/s41467-019-13191-5