Cargando…
MutL sliding clamps coordinate exonuclease-independent Escherichia coli mismatch repair
A shared paradigm of mismatch repair (MMR) across biology depicts extensive exonuclease-driven strand-specific excision that begins at a distant single-stranded DNA (ssDNA) break and proceeds back past the mismatched nucleotides. Historical reconstitution studies concluded that Escherichia coli (Ec)...
Autores principales: | Liu, Jiaquan, Lee, Ryanggeun, Britton, Brooke M., London, James A., Yang, Keunsang, Hanne, Jeungphill, Lee, Jong-Bong, Fishel, Richard |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6876574/ https://www.ncbi.nlm.nih.gov/pubmed/31757945 http://dx.doi.org/10.1038/s41467-019-13191-5 |
Ejemplares similares
-
MutS functions as a clamp loader by positioning MutL on the DNA during mismatch repair
por: Yang, Xiao-Wen, et al.
Publicado: (2022) -
Exploiting the distinctive properties of the bacterial and human MutS homolog sliding clamps on mismatched DNA
por: Britton, Brooke M., et al.
Publicado: (2022) -
MutS/MutL crystal structure reveals that the MutS sliding clamp loads MutL onto DNA
por: Groothuizen, Flora S, et al.
Publicado: (2015) -
The sliding clamp tethers the endonuclease domain of MutL to DNA
por: Pillon, Monica C., et al.
Publicado: (2015) -
Binding of the regulatory domain of MutL to the sliding β-clamp is species specific
por: Almawi, Ahmad W, et al.
Publicado: (2019)