Vaccinia Virus Ankyrin-Repeat/F-Box Protein Targets Interferon-Induced IFITs for Proteasomal Degradation

IFITs are interferon-induced proteins that can bind 5′-triphosphate or ribose-unmethylated capped ends of mRNA to inhibit translation. Although some viruses avoid IFITs by synthesizing RNAs with eukaryotic-like caps, no viral proteins were known to antagonize IFITs. We show that the N- and C-termina...

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Detalles Bibliográficos
Autores principales: Liu, Ruikang, Olano, Lisa R., Mirzakhanyan, Yeva, Gershon, Paul D., Moss, Bernard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6876622/
https://www.ncbi.nlm.nih.gov/pubmed/31644906
http://dx.doi.org/10.1016/j.celrep.2019.09.039

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6876622/
https://www.ncbi.nlm.nih.gov/pubmed/31644906
http://dx.doi.org/10.1016/j.celrep.2019.09.039

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