Optogenetic gamma stimulation rescues memory impairments in an Alzheimer’s disease mouse model

Slow gamma oscillations (30–60 Hz) correlate with retrieval of spatial memory. Altered slow gamma oscillations have been observed in Alzheimer’s disease. Here, we use the J20-APP AD mouse model that displays spatial memory loss as well as reduced slow gamma amplitude and phase-amplitude coupling to...

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Detalles Bibliográficos
Autores principales: Etter, Guillaume, van der Veldt, Suzanne, Manseau, Frédéric, Zarrinkoub, Iman, Trillaud-Doppia, Emilie, Williams, Sylvain
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6876640/
https://www.ncbi.nlm.nih.gov/pubmed/31757962
http://dx.doi.org/10.1038/s41467-019-13260-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6876640/
https://www.ncbi.nlm.nih.gov/pubmed/31757962
http://dx.doi.org/10.1038/s41467-019-13260-9

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