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Integrating spatiotemporal features of a ligand-regulated, multi-state allosteric protein

Dynamic protein molecules are defined by their spatiotemporal characteristics and should thus be represented by models incorporating both characteristics. Structural biology enables determination of atomic structures of individual conformational states of a given protein. Obtaining the complementary...

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Detalles Bibliográficos
Autores principales: Lewis, John H., Lu, Zhe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6876687/
https://www.ncbi.nlm.nih.gov/pubmed/31488908
http://dx.doi.org/10.1038/s41594-019-0276-0