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Mitofusin 2 in Mature Adipocytes Controls Adiposity and Body Weight

We found that exposure of adult animals to caloriedense foods rapidly abolished expression of mitofusin 2 (Mfn2), a gene promoting mitochondrial fusion and mitochondrion-endoplasmic reticulum interactions, in white and brown fat. Mfn2 mRN was also robustly lower in obese human subjects compared with...

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Detalles Bibliográficos
Autores principales: Mancini, Giacomo, Pirruccio, Kevin, Yang, Xiaoyong, Blücher, Matthias, Rodeheffer, Matthew, Horvath, Tamas L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6876693/
https://www.ncbi.nlm.nih.gov/pubmed/30865877
http://dx.doi.org/10.1016/j.celrep.2019.02.039