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Mitofusin 2 in Mature Adipocytes Controls Adiposity and Body Weight
We found that exposure of adult animals to caloriedense foods rapidly abolished expression of mitofusin 2 (Mfn2), a gene promoting mitochondrial fusion and mitochondrion-endoplasmic reticulum interactions, in white and brown fat. Mfn2 mRN was also robustly lower in obese human subjects compared with...
Autores principales: | Mancini, Giacomo, Pirruccio, Kevin, Yang, Xiaoyong, Blücher, Matthias, Rodeheffer, Matthew, Horvath, Tamas L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6876693/ https://www.ncbi.nlm.nih.gov/pubmed/30865877 http://dx.doi.org/10.1016/j.celrep.2019.02.039 |
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