Sumoylation of the DNA polymerase ε by the Smc5/6 complex contributes to DNA replication

DNA polymerase epsilon (Pol ε) is critical for genome duplication, but little is known about how post-translational modification regulates its function. Here we report that the Pol ε catalytic subunit Pol2 in yeast is sumoylated at a single lysine within a catalytic domain insertion uniquely possess...

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Detalles Bibliográficos
Autores principales: Meng, Xiangzhou, Wei, Lei, Peng, Xiao P., Zhao, Xiaolan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6876774/
https://www.ncbi.nlm.nih.gov/pubmed/31765372
http://dx.doi.org/10.1371/journal.pgen.1008426

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6876774/
https://www.ncbi.nlm.nih.gov/pubmed/31765372
http://dx.doi.org/10.1371/journal.pgen.1008426

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