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Sumoylation of the DNA polymerase ε by the Smc5/6 complex contributes to DNA replication
DNA polymerase epsilon (Pol ε) is critical for genome duplication, but little is known about how post-translational modification regulates its function. Here we report that the Pol ε catalytic subunit Pol2 in yeast is sumoylated at a single lysine within a catalytic domain insertion uniquely possess...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6876774/ https://www.ncbi.nlm.nih.gov/pubmed/31765372 http://dx.doi.org/10.1371/journal.pgen.1008426 |