Upregulation of ERK phosphorylation in rat dorsal root ganglion neurons contributes to oxaliplatin-induced chronic neuropathic pain

Oxaliplatin is the first-line chemotherapy for metastatic colorectal cancer. Unlike other platinum anticancer agents, oxaliplatin does not result in significant renal impairment and ototoxicity. Oxaliplatin, however, has been associated with acute and chronic peripheral neuropathies. Despite the awa...

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Detalles Bibliográficos
Autores principales: Maruta, Toyoaki, Nemoto, Takayuki, Hidaka, Koutaro, Koshida, Tomohiro, Shirasaka, Tetsuro, Yanagita, Toshihiko, Takeya, Ryu, Tsuneyoshi, Isao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6876879/
https://www.ncbi.nlm.nih.gov/pubmed/31765435
http://dx.doi.org/10.1371/journal.pone.0225586

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6876879/
https://www.ncbi.nlm.nih.gov/pubmed/31765435
http://dx.doi.org/10.1371/journal.pone.0225586

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