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Quantifying pluripotency landscape of cell differentiation from scRNA-seq data by continuous birth-death process
Modeling cell differentiation from omics data is an essential problem in systems biology research. Although many algorithms have been established to analyze scRNA-seq data, approaches to infer the pseudo-time of cells or quantify their potency have not yet been satisfactorily solved. Here, we propos...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6876891/ https://www.ncbi.nlm.nih.gov/pubmed/31721764 http://dx.doi.org/10.1371/journal.pcbi.1007488 |