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Sequential somatic mutations upon secondary anti-HER2 treatment resistance in metastatic ERBB2(S310F) mutated extramammary Paget’s disease

Metastatic extramammary Paget’s disease is a rare adenocarcinoma with poor prognosis. Several reports of human epidermal growth factor receptor 2 alterations point to its pathogenic role in the disease. However, the occurrence of treatment resistance to anti-HER2 therapy demand the need for further...

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Detalles Bibliográficos
Autores principales: Nordmann, Thierry M., Messerli-Odermatt, Olivia, Meier, Larissa, Micaletto, Sara, Coppetti, Thomas, Nägeli, Mirjam, Kamarachev, Jivko, Kudura, Ken, Freiberger, Sandra N., Rordorf, Tamara, Mangana, Joanna, Braun, Ralph, Dummer, Reinhard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6877105/
https://www.ncbi.nlm.nih.gov/pubmed/31803359
http://dx.doi.org/10.18632/oncotarget.27272