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Apolipoprotein M-bound sphingosine-1-phosphate regulates blood–brain barrier paracellular permeability and transcytosis
The blood-brain barrier (BBB) is formed by the endothelial cells lining cerebral microvessels, but how blood-borne signaling molecules influence permeability is incompletely understood. We here examined how the apolipoprotein M (apoM)-bound sphingosine 1–phosphate (S1P) signaling pathway affects the...
Autores principales: | Mathiesen Janiurek, Mette, Soylu-Kucharz, Rana, Christoffersen, Christina, Kucharz, Krzysztof, Lauritzen, Martin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6877292/ https://www.ncbi.nlm.nih.gov/pubmed/31763978 http://dx.doi.org/10.7554/eLife.49405 |
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