Proton Pump Inhibitors Modulate Transport Of Doxorubicin And Its Liposomal Form Into 2D And 3D Breast Cancer Cell Cultures

PURPOSE: The purpose of our study was to evaluate the influence of two PPIs (omeprazole (OME) and lansoprazole (LANSO)) on weakly basic anticancer drug doxorubicin (DOX) and pegylated liposomal doxorubicin (PLD) delivery to monolayer-cultured 4T1 murine breast cancer cells and tumor spheroids. METHO...

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Detalles Bibliográficos
Autores principales: Paškevičiūtė, Miglė, Petrikaitė, Vilma
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2019
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6877465/
https://www.ncbi.nlm.nih.gov/pubmed/31819614
http://dx.doi.org/10.2147/CMAR.S224097

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6877465/
https://www.ncbi.nlm.nih.gov/pubmed/31819614
http://dx.doi.org/10.2147/CMAR.S224097

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