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Combining alpha radiation-based brachytherapy with immunomodulators promotes complete tumor regression in mice via tumor-specific long-term immune response

Diffusing alpha-emitters radiation therapy (DaRT) is the only known method for treating solid tumors with highly destructive alpha radiation. More importantly, as a monotherapy, DaRT has been shown to induce a systemic antitumor immune response following tumor ablation. Here, immunomodulatory strate...

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Detalles Bibliográficos
Autores principales: Domankevich, Vered, Cohen, Adi, Efrati, Margalit, Schmidt, Michael, Rammensee, Hans-Georg, Nair, Sujit S., Tewari, Ashutosh, Kelson, Itzhak, Keisari, Yona
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6877484/
https://www.ncbi.nlm.nih.gov/pubmed/31637474
http://dx.doi.org/10.1007/s00262-019-02418-5