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Kindlin-2 suppresses transcription factor GATA4 through interaction with SUV39H1 to attenuate hypertrophy

Kindlin-2 plays an important role in the regulation of cardiac structure and function. Depletion of Kindlin-2 contributes to cardiac hypertrophy and progressive heart failure, however, the precise mechanisms involved in this process remain unclear. GATA4 is a critical transcription factor in regulat...

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Detalles Bibliográficos
Autores principales: Qi, Lihua, Chi, Xiaochun, Zhang, Xi, Feng, Xueqian, Chu, Wenhui, Zhang, Shengchang, Wu, Junzhou, Song, Yao, Zhang, Youyi, Kong, Wei, Yu, Yu, Zhang, Hongquan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6877536/
https://www.ncbi.nlm.nih.gov/pubmed/31767831
http://dx.doi.org/10.1038/s41419-019-2121-0