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Assembly of chromosome-scale contigs by efficiently resolving repetitive sequences with long reads
The abundant repetitive sequences in complex eukaryotic genomes cause fragmented assemblies, which lose value as reference genomes, often due to incomplete gene sequences and unanchored or mispositioned contigs on chromosomes. Here we report a genome assembly method HERA, which resolves repeats effi...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6877557/ https://www.ncbi.nlm.nih.gov/pubmed/31767853 http://dx.doi.org/10.1038/s41467-019-13355-3 |