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Identification of novel genetic variants predisposing to familial oral squamous cell carcinomas

Oral squamous cell carcinoma (OSCC) is a common subtype of head and neck squamous cell carcinoma (HNSCC), but the pathogenesis underlying familial OSCCs is unknown. Here, we analyzed whole-genome sequences of a family with autosomal dominant expression of oral tongue cancer and identified proto-onco...

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Detalles Bibliográficos
Autores principales: Huang, Yaping, Zhao, Jizhi, Mao, Guogen, Lee, Grace Sanghee, Zhang, Jia, Bi, Lijun, Gu, Liya, Chang, Zhijie, Valentino, Joseph, Li, Guo-Min
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6877579/
https://www.ncbi.nlm.nih.gov/pubmed/31798960
http://dx.doi.org/10.1038/s41421-019-0126-6