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Schwann cells support oncogenic potential of pancreatic cancer cells through TGFβ signaling

Pancreatic ductal adenocarcinoma (PDAC) is one of the solid tumors with the poorest prognosis. The stroma of this tumor is abundant and composed of extracellular matrix and stromal cells (including cancer-associated fibroblasts and immune cells). Nerve fibers invading this stroma represent a hallmar...

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Detalles Bibliográficos
Autores principales: Roger, Elodie, Martel, Sylvie, Bertrand-Chapel, Adrien, Depollier, Arnaud, Chuvin, Nicolas, Pommier, Roxane M., Yacoub, Karam, Caligaris, Cassandre, Cardot-Ruffino, Victoire, Chauvet, Véronique, Aires, Sophie, Mohkam, Kayvan, Mabrut, Jean-Yves, Adham, Mustapha, Fenouil, Tanguy, Hervieu, Valérie, Broutier, Laura, Castets, Marie, Neuzillet, Cindy, Cassier, Philippe A., Tomasini, Richard, Sentis, Stéphanie, Bartholin, Laurent
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6877617/
https://www.ncbi.nlm.nih.gov/pubmed/31767842
http://dx.doi.org/10.1038/s41419-019-2116-x