Heritability of skewed X-inactivation in female twins is tissue-specific and associated with age

Female somatic X-chromosome inactivation (XCI) balances the X-linked transcriptional dosages between the sexes. Skewed XCI toward one parental X has been observed in several complex human traits, but the extent to which genetics and environment influence skewed XCI is largely unexplored. To address...

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Detalles Bibliográficos
Autores principales: Zito, Antonino, Davies, Matthew N., Tsai, Pei-Chien, Roberts, Susanna, Andres-Ejarque, Rosa, Nardone, Stefano, Bell, Jordana T., Wong, Chloe C. Y., Small, Kerrin S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6877649/
https://www.ncbi.nlm.nih.gov/pubmed/31767861
http://dx.doi.org/10.1038/s41467-019-13340-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6877649/
https://www.ncbi.nlm.nih.gov/pubmed/31767861
http://dx.doi.org/10.1038/s41467-019-13340-w

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