Hepatocyte gene expression and DNA methylation as ancestry-dependent mechanisms in African Americans

African Americans (AAs) are an admixed population with widely varying proportion of West African ancestry (WAA). Here we report the correlation of WAA to gene expression and DNA methylation in AA-derived hepatocytes, a cell type important in disease and drug response. We perform mediation analysis t...

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Detalles Bibliográficos
Autores principales: Park, C. S., De, T., Xu, Y., Zhong, Y., Smithberger, E., Alarcon, C., Gamazon, E. R., Perera, M. A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6877651/
https://www.ncbi.nlm.nih.gov/pubmed/31798965
http://dx.doi.org/10.1038/s41525-019-0102-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6877651/
https://www.ncbi.nlm.nih.gov/pubmed/31798965
http://dx.doi.org/10.1038/s41525-019-0102-y

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