(11)C-Labeled Pictilisib (GDC-0941) as a Molecular Tracer Targeting Phosphatidylinositol 3-Kinase (PI3K) for Breast Cancer Imaging

Pictilisib (GDC-0941) is an inhibitor of phosphatidylinositol 3-kinase (PI3K), part of a signaling cascade involved in breast cancer development. The purpose of this study was to evaluate the pharmacokinetics of pictilisib noninvasively by radiolabeling it with (11)C and to assess the usability of t...

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Detalles Bibliográficos
Autores principales: Han, Na, Jiang, Yaqun, Gai, Yongkang, Liu, Qingyao, Yuan, Lujie, Wang, Yichun, Li, Mengting, Zhang, Yongxue, Lan, Xiaoli
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6877939/
https://www.ncbi.nlm.nih.gov/pubmed/31787861
http://dx.doi.org/10.1155/2019/1760184

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6877939/
https://www.ncbi.nlm.nih.gov/pubmed/31787861
http://dx.doi.org/10.1155/2019/1760184

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