Polyphyllin VII Promotes Apoptosis and Autophagic Cell Death via ROS-Inhibited AKT Activity, and Sensitizes Glioma Cells to Temozolomide

The high recurrence frequency of gliomas but deficiency of effective treatment and prevalent chemoresistance have elicited interests in exploring and developing new agents. Paris polyphyllins are monomers extracted from rhizome of Paris polyphylla var. yunnanensis. Here, we first reported that polyp...

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Detalles Bibliográficos
Autores principales: Pang, Dejiang, Li, Chao, Yang, Chengcheng, Zou, Yuanfeng, Feng, Bin, Li, Lixia, Liu, Wentao, Geng, Yi, Luo, Qihui, Chen, Zhengli, Huang, Chao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6877958/
https://www.ncbi.nlm.nih.gov/pubmed/31814867
http://dx.doi.org/10.1155/2019/1805635

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6877958/
https://www.ncbi.nlm.nih.gov/pubmed/31814867
http://dx.doi.org/10.1155/2019/1805635

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