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Increased mistranslation protects E. coli from protein misfolding stress due to activation of a RpoS‐dependent heat shock response

The misincorporation of an incorrect amino acid into a polypeptide during protein synthesis is considered a detrimental phenomenon. A mistranslated protein is often misfolded and degraded or nonfunctional and results in an increased cost to quality control machinery. Despite these costs, errors duri...

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Detalles Bibliográficos
Autores principales: Evans, Christopher R., Fan, Yongqiang, Ling, Jiqiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6878130/
https://www.ncbi.nlm.nih.gov/pubmed/31419308
http://dx.doi.org/10.1002/1873-3468.13578