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Withaferin A ameliorates ovarian cancer-induced cachexia and proinflammatory signaling

BACKGROUND: Ovarian cancer is the fifth leading cause of cancer-related deaths amongst women in the United States. Cachexia is the primary cause of death in approximately 30% of cancer patients, and is often evidenced in ovarian cancer patients. We tested the steroidal lactone Withaferin A to examin...

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Detalles Bibliográficos
Autores principales: Straughn, Alex R., Kakar, Sham S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6878639/
https://www.ncbi.nlm.nih.gov/pubmed/31767036
http://dx.doi.org/10.1186/s13048-019-0586-1