BRCA1 mutation influences progesterone response in human benign mammary organoids

BACKGROUND: Women, who carry a germline BRCA1 gene mutation, have a markedly increased risk of developing breast cancer during their lifetime. While BRCA1 carriers frequently develop triple-negative, basal-like, aggressive breast tumors, hormone signaling is important in the genesis of BRCA1 mutant...

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Detalles Bibliográficos
Autores principales: Davaadelger, Batzaya, Choi, Mi-Ran, Singhal, Hari, Clare, Susan E., Khan, Seema A., Kim, J. Julie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6878650/
https://www.ncbi.nlm.nih.gov/pubmed/31771627
http://dx.doi.org/10.1186/s13058-019-1214-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6878650/
https://www.ncbi.nlm.nih.gov/pubmed/31771627
http://dx.doi.org/10.1186/s13058-019-1214-0

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