Cargando…
DNMT3b/OCT4 expression confers sorafenib resistance and poor prognosis of hepatocellular carcinoma through IL-6/STAT3 regulation
BACKGROUND: The inflammatory cytokine interleukin-6 (IL-6) is critical for the expression of octamer-binding transcription factor 4 (OCT4), which is highly associated with early tumor recurrence and poor prognosis of hepatocellular carcinomas (HCC). DNA methyltransferase (DNMT) family is closely lin...
Autores principales: | Lai, Ssu-Chuan, Su, Yu-Ting, Chi, Ching-Chi, Kuo, Yung-Che, Lee, Kam-Fai, Wu, Yu-Chih, Lan, Pei-Chi, Yang, Muh-Hwa, Chang, Te-Sheng, Huang, Yen-Hua |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6878666/ https://www.ncbi.nlm.nih.gov/pubmed/31771617 http://dx.doi.org/10.1186/s13046-019-1442-2 |
Ejemplares similares
-
Correction to: DNMT3b/OCT4 expression confers sorafenib resistance and poor prognosis of hepatocellular carcinoma through IL-6/STAT3 regulation
por: Lai, Ssu-Chuan, et al.
Publicado: (2020) -
The STAT3-DNMT1 connection
por: Thomas, N. Shaun B.
Publicado: (2012) -
DNMT3a promotes proliferation by activating the STAT3 signaling pathway and depressing apoptosis in pancreatic cancer
por: Jing, Wei, et al.
Publicado: (2019) -
Novel sorafenib analogues induce apoptosis through SHP-1 dependent STAT3 inactivation in human breast cancer cells
por: Liu, Chun-Yu, et al.
Publicado: (2013) -
TGF-βI Regulates Cell Migration through Pluripotent Transcription Factor OCT4 in Endometriosis
por: Au, Heng-Kien, et al.
Publicado: (2015)