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Mapping the Lineage Relationship between CXCR5(+) and CXCR5(−) CD4(+) T Cells in HIV-Infected Human Lymph Nodes

CXCR5 is a key marker of follicular helper T (T(FH)) cells. Using primary lymph nodes (LNs) from HIV-infected patients, we identified a population of CXCR5(−) CD4(+) T cells with T(FH)-cell-like features. This CXCR5(−) subset becomes expanded in severe HIV infection and is characterized by the upreg...

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Detalles Bibliográficos
Autores principales: Del Alcazar, Daniel, Wang, Yifeng, He, Chenfeng, Wendel, Ben S., Del Río-Estrada, Perla M., Lin, Jerome, Ablanedo-Terrazas, Yuria, Malone, Michael J., Hernandez, Stefany M., Frank, Ian, Naji, Ali, Reyes-Terán, Gustavo, Jiang, Ning, Su, Laura F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6878759/
https://www.ncbi.nlm.nih.gov/pubmed/31533030
http://dx.doi.org/10.1016/j.celrep.2019.08.037