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Mapping the Lineage Relationship between CXCR5(+) and CXCR5(−) CD4(+) T Cells in HIV-Infected Human Lymph Nodes
CXCR5 is a key marker of follicular helper T (T(FH)) cells. Using primary lymph nodes (LNs) from HIV-infected patients, we identified a population of CXCR5(−) CD4(+) T cells with T(FH)-cell-like features. This CXCR5(−) subset becomes expanded in severe HIV infection and is characterized by the upreg...
Autores principales: | , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6878759/ https://www.ncbi.nlm.nih.gov/pubmed/31533030 http://dx.doi.org/10.1016/j.celrep.2019.08.037 |