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The Role of Cathepsin B in Peritoneal Fibrosis due to Peritoneal Dialysis

Glucose-containing peritoneal dialysis (PD) solution causes peritoneal fibrosis (PF) characterized by accumulation of extracellular matrix (ECM) in the submesothelial layer. Cathepsin B is a lysosomal cysteine protease that degrades ECM, but its role in the PF remains unclear. Thus, we investigated...

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Detalles Bibliográficos
Autores principales: Sung, Su Ah, Kim, Dong Hee, Oh, Kook-Hwan, Han, Sang Youb, Han, Kum Hyun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6878782/
https://www.ncbi.nlm.nih.gov/pubmed/31815017
http://dx.doi.org/10.1155/2019/4150656