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DAZL Regulates Germ Cell Survival through a Network of PolyA-Proximal mRNA Interactions
The RNA binding protein DAZL is essential for gametogenesis, but its direct in vivo functions, RNA targets, and the molecular basis for germ cell loss in Dazl-null mice are unknown. Here, we mapped transcriptome-wide DAZL-RNA interactions in vivo, revealing DAZL binding to thousands of mRNAs via pol...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6878787/ https://www.ncbi.nlm.nih.gov/pubmed/30380414 http://dx.doi.org/10.1016/j.celrep.2018.10.012 |