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Mapping the Germline and Somatic Mutation Interaction Landscape in Indolent and Aggressive Prostate Cancers

BACKGROUND: A majority of prostate cancers (PCas) are indolent and cause no harm even without treatment. However, a significant proportion of patients with PCa have aggressive tumors that progress rapidly to metastatic disease and are often lethal. PCa develops through somatic mutagenesis, but emerg...

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Detalles Bibliográficos
Autores principales: Mamidi, Tarun Karthik Kumar, Wu, Jiande, Hicks, Chindo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6878815/
https://www.ncbi.nlm.nih.gov/pubmed/31814827
http://dx.doi.org/10.1155/2019/4168784