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Mapping the Germline and Somatic Mutation Interaction Landscape in Indolent and Aggressive Prostate Cancers
BACKGROUND: A majority of prostate cancers (PCas) are indolent and cause no harm even without treatment. However, a significant proportion of patients with PCa have aggressive tumors that progress rapidly to metastatic disease and are often lethal. PCa develops through somatic mutagenesis, but emerg...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6878815/ https://www.ncbi.nlm.nih.gov/pubmed/31814827 http://dx.doi.org/10.1155/2019/4168784 |