Sirt5 Attenuates Cisplatin-Induced Acute Kidney Injury through Regulation of Nrf2/HO-1 and Bcl-2

Cisplatin- (CDDP) induced acute kidney injury (AKI) limits the clinical use of cisplatin. Several sirtuin (SIRT) family proteins are involved in AKI, while the roles of Sirt5 in cisplatin-induced AKI remain unknown. In the present study, we characterized the role and mechanism of Sirt5 in cisplatin-...

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Detalles Bibliográficos
Autores principales: Li, Wei, Yang, Yuanyuan, Li, You, Zhao, Yueyue, Jiang, Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6878818/
https://www.ncbi.nlm.nih.gov/pubmed/31815138
http://dx.doi.org/10.1155/2019/4745132

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6878818/
https://www.ncbi.nlm.nih.gov/pubmed/31815138
http://dx.doi.org/10.1155/2019/4745132

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