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Sirt5 Attenuates Cisplatin-Induced Acute Kidney Injury through Regulation of Nrf2/HO-1 and Bcl-2

Cisplatin- (CDDP) induced acute kidney injury (AKI) limits the clinical use of cisplatin. Several sirtuin (SIRT) family proteins are involved in AKI, while the roles of Sirt5 in cisplatin-induced AKI remain unknown. In the present study, we characterized the role and mechanism of Sirt5 in cisplatin-...

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Detalles Bibliográficos
Autores principales:	Li, Wei, Yang, Yuanyuan, Li, You, Zhao, Yueyue, Jiang, Hong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2019
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6878818/ https://www.ncbi.nlm.nih.gov/pubmed/31815138 http://dx.doi.org/10.1155/2019/4745132

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