Cargando…

Sirt5 Attenuates Cisplatin-Induced Acute Kidney Injury through Regulation of Nrf2/HO-1 and Bcl-2

Cisplatin- (CDDP) induced acute kidney injury (AKI) limits the clinical use of cisplatin. Several sirtuin (SIRT) family proteins are involved in AKI, while the roles of Sirt5 in cisplatin-induced AKI remain unknown. In the present study, we characterized the role and mechanism of Sirt5 in cisplatin-...

Descripción completa

Detalles Bibliográficos
Autores principales: Li, Wei, Yang, Yuanyuan, Li, You, Zhao, Yueyue, Jiang, Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6878818/
https://www.ncbi.nlm.nih.gov/pubmed/31815138
http://dx.doi.org/10.1155/2019/4745132

Ejemplares similares