Identification of TYW3/CRYZ and FGD4 as susceptibility genes for amyotrophic lateral sclerosis

OBJECTIVE: A 2-stage genome-wide association was conducted to explore the genetic etiology of amyotrophic lateral sclerosis (ALS) in the Chinese Han population. METHODS: Totally, 700 cases and 4,027 controls were genotyped in the discovery stage using Illumina Human660W-Quad BeadChips. Top associate...

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Detalles Bibliográficos
Autores principales: Wei, Ling, Tian, Yanghua, Chen, Yongping, Wei, Qianqian, Chen, Fangfang, Cao, Bei, Wu, Ying, Zhao, Bi, Chen, Xueping, Xie, Chengjuan, Xi, Chunhua, Yu, Xu'en, Wang, Juan, Lv, Xinyi, Du, Jing, Wang, Yu, Shen, Lu, Wang, Xin, Shen, Bin, Guo, Qihao, Guo, Li, Xia, Kun, Xie, Peng, Zhang, Xuejun, Zuo, Xianbo, Shang, Huifang, Wang, Kai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6878836/
https://www.ncbi.nlm.nih.gov/pubmed/31872054
http://dx.doi.org/10.1212/NXG.0000000000000375

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6878836/
https://www.ncbi.nlm.nih.gov/pubmed/31872054
http://dx.doi.org/10.1212/NXG.0000000000000375

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