Calcium Pyrophosphate And Monosodium Urate Activate The NLRP3 Inflammasome Within Bladder Urothelium Via Reactive Oxygen Species And TXNIP

OBJECTIVE: To investigate the in vitro activation of the NLRP3 inflammasome within bladder urothelium by stone-forming components. Further, to describe the contributions of reactive oxygen species (ROS) and thioredoxin-interacting protein (TXNIP), an important structural component of the inflammasom...

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Detalles Bibliográficos
Autores principales: Harper, Shelby N, Leidig, Patrick D, Hughes, Francis M, Jin, Huixia, Purves, J Todd
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2019
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6879004/
https://www.ncbi.nlm.nih.gov/pubmed/31819864
http://dx.doi.org/10.2147/RRU.S225767

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6879004/
https://www.ncbi.nlm.nih.gov/pubmed/31819864
http://dx.doi.org/10.2147/RRU.S225767

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