Cargando…

Calcium Pyrophosphate And Monosodium Urate Activate The NLRP3 Inflammasome Within Bladder Urothelium Via Reactive Oxygen Species And TXNIP

OBJECTIVE: To investigate the in vitro activation of the NLRP3 inflammasome within bladder urothelium by stone-forming components. Further, to describe the contributions of reactive oxygen species (ROS) and thioredoxin-interacting protein (TXNIP), an important structural component of the inflammasom...

Descripción completa

Detalles Bibliográficos
Autores principales:	Harper, Shelby N, Leidig, Patrick D, Hughes, Francis M, Jin, Huixia, Purves, J Todd
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove 2019
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6879004/ https://www.ncbi.nlm.nih.gov/pubmed/31819864 http://dx.doi.org/10.2147/RRU.S225767

Ejemplares similares

Ethanol Augments Monosodium Urate-Induced NLRP3 Inflammasome Activation via Regulation of AhR and TXNIP in Human Macrophages
por: Kim, Seong-Kyu, et al.
Publicado: (2020)

Protocol for in vivo and in vitro activation of NLRP3 inflammasome in mice using monosodium urate
por: Liu, Didi, et al.
Publicado: (2023)

Lower Temperatures Exacerbate NLRP3 Inflammasome Activation by Promoting Monosodium Urate Crystallization, Causing Gout
por: Ahn, Huijeong, et al.
Publicado: (2021)

Kv1.5 channel mediates monosodium urate-induced activation of NLRP3 inflammasome in macrophages and arrhythmogenic effects of urate on cardiomyocytes
por: Li, Peili, et al.
Publicado: (2022)

Ameliorative Effects of Cardamonin on Monosodium Urate-Induced Gouty Arthritis through Inhibiting NLRP3 Inflammasome Mediation
por: Wang, Chih-Chien, et al.
Publicado: (2021)

Monosodium Urate Crystals Activate the Inflammasome in Primary Progressive Multiple Sclerosis
por: Piancone, Federica, et al.
Publicado: (2018)

Regulatory T cells induced by B cells suppress NLRP3 inflammasome activation and alleviate monosodium urate-induced gouty inflammation
por: Huang, Jing-Hui, et al.
Publicado: (2021)

Inflammation triggered by the NLRP3 inflammasome is a critical driver of diabetic bladder dysfunction
por: Hughes, Francis M., et al.
Publicado: (2022)

Role of the NLRP3 inflammasome in the transient release of IL-1β induced by monosodium urate crystals in human fibroblast-like synoviocytes
por: Zheng, Shu-cong, et al.
Publicado: (2015)

Crocin Attenuates NLRP3 Inflammasome Activation by Inhibiting Mitochondrial Reactive Oxygen Species and Ameliorates Monosodium Urate-Induced Mouse Peritonitis
por: Sangare, Ruth, et al.
Publicado: (2023)

Immunosuppression by piperine as a regulator of the NLRP3 inflammasome through MAPK/NF-κB in monosodium urate-induced rat gouty arthritis
por: Jati, Galih Aji Kuncoro, et al.
Publicado: (2022)

(−)-Epicatechin Ameliorates Monosodium Urate-Induced Acute Gouty Arthritis Through Inhibiting NLRP3 Inflammasome and the NF-κB Signaling Pathway
por: Wu, Chenxi, et al.
Publicado: (2022)

DIFFERENTIAL MEMBRANOLYTIC EFFECTS OF MICROCRYSTALLINE SODIUM URATE AND CALCIUM PYROPHOSPHATE DIHYDRATE
por: Wallingford, Walter R., et al.
Publicado: (1971)

Decoy Receptor 3 Inhibits Monosodium Urate-Induced NLRP3 Inflammasome Activation via Reduction of Reactive Oxygen Species Production and Lysosomal Rupture
por: Pan, Yi-Gen, et al.
Publicado: (2021)

Cichoric Acid Ameliorates Monosodium Urate-Induced Inflammatory Response by Reducing NLRP3 Inflammasome Activation via Inhibition of NF-kB Signaling Pathway
por: Wang, Qi, et al.
Publicado: (2021)

Role of ASM/Cer/TXNIP signaling module in the NLRP3 inflammasome activation
por: Jiang, Jianjun, et al.
Publicado: (2021)

The Protective Effects of Neoastilbin on Monosodium Urate Stimulated THP-1-Derived Macrophages and Gouty Arthritis in Mice through NF-κB and NLRP3 Inflammasome Pathways
por: Xu, Wenjing, et al.
Publicado: (2022)

microRNA-223 Deficiency Exacerbates Acute Inflammatory Response to Monosodium Urate Crystals by Targeting NLRP3
por: Yang, Qi-Bin, et al.
Publicado: (2021)

AB279. SPR-06 Fibrosis in the bladder in response to outlet obstruction is triggered through the NLRP3 inflammasome and the production of IL-1β
por: Hughes, Francis M., et al.
Publicado: (2016)

Pro-Inflammatory of PRDM1/SIRT2/NLRP3 Axis in Monosodium Urate-Induced Acute Gouty Arthritis
por: Zhao, Qingsong, et al.
Publicado: (2023)

Corilagin Restrains NLRP3 Inflammasome Activation and Pyroptosis through the ROS/TXNIP/NLRP3 Pathway to Prevent Inflammation
por: Luo, Tianyu, et al.
Publicado: (2022)

Monosodium urate crystals induce oxidative stress in human synoviocytes
por: Zamudio-Cuevas, Yessica, et al.
Publicado: (2016)

The Role of Inhibitory Receptors in Monosodium Urate Crystal-Induced Inflammation
por: Fernandes, Maria J., et al.
Publicado: (2018)

Monosodium Urate Contributes to Retinal Inflammation and Progression of Diabetic Retinopathy
por: Thounaojam, Menaka C., et al.
Publicado: (2019)

Cynarin suppresses gouty arthritis induced by monosodium urate crystals
por: Wu, Changgui, et al.
Publicado: (2022)

Effects of Hypoxic Environment on Periodontal Tissue through the ROS/TXNIP/NLRP3 Inflammasome Pathway
por: Zhu, Rui, et al.
Publicado: (2022)

Expression and Mechanism of TXNIP/NLRP3 Inflammasome in Sciatic Nerve of Type 2 Diabetic Rats
por: Han, Le, et al.
Publicado: (2022)

HMG-CoA Reductase Inhibitors Suppress Monosodium Urate-Induced NLRP3 Inflammasome Activation through Peroxisome Proliferator-Activated Receptor-γ Activation in THP-1 Cells
por: Kim, Seong-Kyu, et al.
Publicado: (2023)

High Glucose and Lipopolysaccharide Prime NLRP3 Inflammasome via ROS/TXNIP Pathway in Mesangial Cells
por: Feng, Hong, et al.
Publicado: (2016)

Honokiol antagonizes doxorubicin-induced cardiomyocyte senescence by inhibiting TXNIP-mediated NLRP3 inflammasome activation
por: Huang, Pian-Pian, et al.
Publicado: (2020)

SIRT1 Inhibits High Glucose–Induced TXNIP/NLRP3 Inflammasome Activation and Cataract Formation
por: Lian, Lili, et al.
Publicado: (2023)

Raman Spectroscopy Applied to the Noninvasive Detection of Monosodium Urate Crystal Deposits
por: Curran, Declan J, et al.
Publicado: (2015)

Monosodium Urate Crystal-Induced Chondrocyte Death via Autophagic Process
por: Hwang, Hyun Sook, et al.
Publicado: (2015)

Factors influencing the crystallization of monosodium urate: a systematic literature review
por: Chhana, Ashika, et al.
Publicado: (2015)

Osteogenic Potential of Monosodium Urate Crystals in Synovial Mesenchymal Stem Cells
por: Martínez-Flores, Karina, et al.
Publicado: (2022)

Effects of Berberine on NLRP3 and IL-1β Expressions in Monocytic THP-1 Cells with Monosodium Urate Crystals-Induced Inflammation
por: Liu, Ya-Fei, et al.
Publicado: (2016)

Inhibition of the PERK/TXNIP/NLRP3 Axis by Baicalin Reduces NLRP3 Inflammasome-Mediated Pyroptosis in Macrophages Infected with Mycobacterium tuberculosis
por: Fu, Yan, et al.
Publicado: (2021)

N-Lobe of TXNIP Is Critical in the Allosteric Regulation of NLRP3 via TXNIP Binding
por: Cheng, Fengyu, et al.
Publicado: (2022)

PARP-1 regulates inflammasome activity by poly-ADP-ribosylation of NLRP3 and interaction with TXNIP in primary macrophages
por: Chiu, Ling-Ya, et al.
Publicado: (2022)

BCG Induced Necrosis of the Entire Bladder Urothelium
por: Krönig, Malte, et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_u8hst5gbjefl70rjpuf9dpsosi