Activation of Shigella flexneri type 3 secretion requires a host-induced conformational change to the translocon pore

Type 3 secretion systems (T3SSs) are conserved bacterial nanomachines that inject virulence proteins (effectors) into eukaryotic cells during infection. Due to their ability to inject heterologous proteins into human cells, these systems are being developed as therapeutic delivery devices. The T3SS...

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Detalles Bibliográficos
Autores principales: Russo, Brian C., Duncan, Jeffrey K., Wiscovitch, Alexandra L., Hachey, Austin C., Goldberg, Marcia B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6879154/
https://www.ncbi.nlm.nih.gov/pubmed/31725799
http://dx.doi.org/10.1371/journal.ppat.1007928

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6879154/
https://www.ncbi.nlm.nih.gov/pubmed/31725799
http://dx.doi.org/10.1371/journal.ppat.1007928

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