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The in vivo ISGylome links ISG15 to metabolic pathways and autophagy upon Listeria monocytogenes infection
ISG15 is an interferon-stimulated, ubiquitin-like protein, with anti-viral and anti-bacterial activity. Here, we map the endogenous in vivo ISGylome in the liver following Listeria monocytogenes infection by combining murine models of reduced or enhanced ISGylation with quantitative proteomics. Our...
Autores principales: | , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6879477/ https://www.ncbi.nlm.nih.gov/pubmed/31772204 http://dx.doi.org/10.1038/s41467-019-13393-x |