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Multi-dimensional computational pipeline for large-scale deep screening of compound effect assessment: an in silico case study on ageing-related compounds

Designing alternative approaches to efficiently screen chemicals on the efficacy landscape is a challenging yet indispensable task in the current compound profiling methods. Particularly, increasing regulatory restrictions underscore the need to develop advanced computational pipelines for efficacy...

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Detalles Bibliográficos
Autores principales: Gupta, Vipul, Crudu, Alina, Matsuoka, Yukiko, Ghosh, Samik, Rozot, Roger, Marat, Xavier, Jäger, Sibylle, Kitano, Hiroaki, Breton, Lionel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6879499/
https://www.ncbi.nlm.nih.gov/pubmed/31798962
http://dx.doi.org/10.1038/s41540-019-0119-y