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Multi-dimensional computational pipeline for large-scale deep screening of compound effect assessment: an in silico case study on ageing-related compounds
Designing alternative approaches to efficiently screen chemicals on the efficacy landscape is a challenging yet indispensable task in the current compound profiling methods. Particularly, increasing regulatory restrictions underscore the need to develop advanced computational pipelines for efficacy...
Autores principales: | Gupta, Vipul, Crudu, Alina, Matsuoka, Yukiko, Ghosh, Samik, Rozot, Roger, Marat, Xavier, Jäger, Sibylle, Kitano, Hiroaki, Breton, Lionel |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6879499/ https://www.ncbi.nlm.nih.gov/pubmed/31798962 http://dx.doi.org/10.1038/s41540-019-0119-y |
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