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Repression of transcription factor AP-2 alpha by PPARγ reveals a novel transcriptional circuit in basal-squamous bladder cancer

The discovery of bladder cancer transcriptional subtypes provides an opportunity to identify high risk patients, and tailor disease management. Recent studies suggest tumor heterogeneity contributes to regional differences in molecular subtype within the tumor, as well as during progression and foll...

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Detalles Bibliográficos
Autores principales: Yamashita, Hironobu, Kawasawa, Yuka I., Shuman, Lauren, Zheng, Zongyu, Tran, Truc, Walter, Vonn, Warrick, Joshua I., Chen, Guoli, Al-Ahmadie, Hikmat, Kaag, Matthew, Wong, Pak Kin, Raman, Jay D., DeGraff, David J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6879593/
https://www.ncbi.nlm.nih.gov/pubmed/31772149
http://dx.doi.org/10.1038/s41389-019-0178-3