Introducing Patterns of Variability for Overcoming Compensatory Adaptation of the Immune System to Immunomodulatory Agents: A Novel Method for Improving Clinical Response to Anti-TNF Therapies

Primary lack of response and secondary loss of response (LOR) are major obstacles to the use of anti–tumor necrosis factor (TNF)-based therapies in patients with rheumatoid arthritis or inflammatory bowel disease. Here, we review the mechanisms and methods for predicting LOR and the currently used m...

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Detalles Bibliográficos
Autores principales: Khoury, Tawfik, Ilan, Yaron
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6879658/
https://www.ncbi.nlm.nih.gov/pubmed/31824506
http://dx.doi.org/10.3389/fimmu.2019.02726

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6879658/
https://www.ncbi.nlm.nih.gov/pubmed/31824506
http://dx.doi.org/10.3389/fimmu.2019.02726

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